A case study of 10 patients administered HBOC‐201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option

Zumberg, Marc; B. Gorlin, Jed; A. Griffiths, Elizabeth; Schwartz, Garry; S. Fletcher, Bradley; Walsh, Katherine; Dao, Kim‐Hien; M. VanSandt, Amanda; Lynn, Mauricio; Shander, Aryeh

doi:10.1111/trf.15778

Public

A case study of 10 patients administered HBOC‐201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option

Published in Transfusion • May 1, 2020

Authors:

Marc Zumberg

Jed B. Gorlin

Elizabeth A. Griffiths

Abstract

BACKGROUND: Hemoglobin-Based Oxygen Carriers (HBOCs) can act as an "oxygen bridge" in acute severe anemia when transfusion is indicated, but not possible. We present data on 10 Expanded Access (EA) patients treated with high cumulative doses of Hemopure (HBOC-201), to assess the ability of HBOC-201 ...

Subject

Medicine

Anemia

Hemoglobin

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