Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold

MGM, Gomes; MU, Ferreira; RM, Corder; JG, King; C, Souto-Maior; C, Penha-Gonçalves; G, Gonçalves; M, Chikina; W, Pegden; R, Aguas

doi:10.1101/2020.04.27.20081893

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Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold

Shared by NobleBlocks on May 2, 2020 • 12:00 AM UTC

Authors:

Gomes MGM

Ferreira MU

Corder RM

Abstract

Individual variation in susceptibility and exposure is subject to selection by natural infection, accelerating the acquisition of immunity, and reducing herd immunity thresholds and epidemic final sizes. This is a manifestation of a wider population phenomenon known as “frailty variation”. Despite t...

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