Extracellular Vesicles Derived from Neural Progenitor Cells--a Preclinical Evaluation for Stroke Treatment in Mice.

X, Zheng; L, Zhang; Y, Kuang; V, Venkataramani; F, Jin; K, Hein; MP, Zafeiriou; C, Lenz; W, Moebius; E, Kilic; DM, Hermann; MS, Weber; H, Urlaub; WH, Zimmermann; M, Bähr; TR, Doeppner

doi:10.1007/s12975-020-00814-z

Public

Extracellular Vesicles Derived from Neural Progenitor Cells--a Preclinical Evaluation for Stroke Treatment in Mice.

Shared by NobleBlocks on May 2, 2020 • 12:00 AM UTC

Authors:

Zheng X

Zhang L

Kuang Y

Abstract

Stem cells such as mesenchymal stem cells (MSCs) enhance neurological recovery in preclinical stroke models by secreting extracellular vesicles (EVs). Since previous reports have focused on the application of MSC-EVs only, the role of the most suitable host cell for EV enrichment and preclinical str...

Subject

Cerebral ischemia

Neuroregeneration

Neurological Recovery

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