Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice

Zheng, Xuan; Zhang, Lin; Kuang, Yi; Venkataramani, Vivek; Jin, Fengyan; Hein, Katharina; Zafeiriou, Maria-Patapia; Lenz, Christof; Möbius, Wiebke; Kilic, E.; M. Hermann, Dirk; Weber, M.; Urlaub, Henning; Zimmermann, Wolfram‐Hubertus; Bähr, Mathias; R. Doeppner, Thorsten

doi:10.1007/s12975-020-00814-z

Public

Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice

Published in Translational Stroke Research • May 2, 2020

Authors:

Xuan Zheng

Lin Zhang

Yi Kuang

Abstract

Stem cells such as mesenchymal stem cells (MSCs) enhance neurological recovery in preclinical stroke models by secreting extracellular vesicles (EVs). Since previous reports have focused on the application of MSC-EVs only, the role of the most suitable host cell for EV enrichment and preclinical str...

Subject

Extracellular vesicles

Medicine

Neurology

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