Effective treatment of severe COVID-19 patients with tocilizumab

Xu, Xiaoling; Han, Mingfeng; Li, Tiantian; Sun, Wei; Wang, Dongsheng; Fu, Binqing; Zhou, Yonggang; Zheng, Xiaohu; Yang, Yun; Li, Xiuyong; Zhang, Xiao‐Hua; Pan, Aijun; Wei, Haiming

doi:10.1073/pnas.2005615117

Public

Effective treatment of severe COVID-19 patients with tocilizumab

Published in Proceedings of the National Academy of Sciences • Apr 29, 2020

Authors:

Xiaoling Xu

Mingfeng Han

Tiantian Li

Abstract

After analyzing the immune characteristics of patients with severe coronavirus disease 2019 (COVID-19), we have identified that pathogenic T cells and inflammatory monocytes with large amount of interleukin 6 secreting may incite the inflammatory storm, which may potentially be curbed through monocl...

Subject

Tocilizumab

Medicine

Cytokine storm

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