Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke

Yang, Pengfei; Zhang, Yongwei; Zhang, Lei; Zhang, Yongxin; M. Treurniet, Kilian; Chen, Wenhuo; Peng, Ya; Han, Hongxing; Wang, Jiyue; Wang, Shouchun; Yin, Congguo; Liu, Sheng; Wang, Peng; Fang, Qi; Shi, Hongchao; Yang, Jianhong; Wen, Changming; Conghui, Li; Jiang, Changchun; Sun, Junwei; Yue, Xincan; Lou, Min; Zhang, Meng; Shu, Hansheng; Sun, Dianjing; Liang, Hui; Li, Tong; Guo, Fuqiang; Ke, Kaifu; Yuan, Haicheng; Wang, Guoping; Yang, Weimin; Shi, Huaizhang; Li, Tianxiao; Li, Zifu; Xing, Pengfei; Zhang, Ping; Zhou, Yu; Wang, Hao; Xu, Yi; Huang, Qinghai; Wu, Tao; Zhao, Rui; Li, Qiang; Fang, Yibin; Wang, Laixing; Lu, Jianping; Li, Yansheng; Fu, Jianhui; Zhong, Xihua; Wang, Yongjun; Wang, Longde; Goyal, Mayank; W.J. Dippel, Diederik; Hong, Bo; Deng, Benqiang; B.W.E.M. Roos, Yvo; B.L.M. Majoie, Charles; Liu, Jianmin

doi:10.1056/nejmoa2001123

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Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke

Published in New England Journal of Medicine • May 6, 2020

Authors:

Pengfei Yang

Yongwei Zhang

Lei Zhang

Abstract

BACKGROUND: In acute ischemic stroke, there is uncertainty regarding the benefit and risk of administering intravenous alteplase before endovascular thrombectomy. METHODS: We conducted a trial at 41 academic tertiary care centers in China to evaluate endovascular thrombectomy with or without intrave...

Subject

Medicine

Odds ratio

Confidence interval

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