Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs

Jeon, Sangeun; Ko, Meehyun; Lee, Jihye; Choi, Inhee; Young Byun, Soo; Park, Soonju; Shum, David; Kim, Seungtaek

doi:10.1128/aac.00819-20

Public

Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs

Published in Antimicrobial Agents and Chemotherapy • May 5, 2020

Authors:

Sangeun Jeon

Meehyun Ko

Jihye Lee

Abstract

Drug repositioning is the only feasible option to immediately address the COVID-19 global challenge. We screened a panel of 48 FDA-approved drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which were preselected by an assay of SARS-CoV. We identified 24 potential antiviral ...

Subject

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Drug

2019-20 coronavirus outbreak

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