Transplantation of discarded livers following viability testing with normothermic machine perfusion

Mergental, Hynek; W. Laing, Richard; Kirkham, Amanda; Thamara P. R. Perera, M.; L. Boteon, Yuri; Attard, Joseph; Barton, Darren; M. Curbishley, Stuart; Wilkhu, Manpreet; Neil, Desley; G. Hübscher, Stefan; Muiesan, Paolo; Isaac, John; Roberts, Keith; Abradelo, Manuel; Schlegel, Andrea; Ferguson, James; Cilliers, Hentie; Bion, Julian; Adams, David; Morris, C.G.; J. Friend, Peter; Yap, Christina; C. Afford, Simon; F. Mirza, Darius

doi:10.1038/s41467-020-16251-3

Public

Transplantation of discarded livers following viability testing with normothermic machine perfusion

Published in Nature Communications • Jun 16, 2020

Authors:

Hynek Mergental

Richard W. Laing

Amanda Kirkham

Abstract

There is a limited access to liver transplantation, however, many organs are discarded based on subjective assessment only. Here we report the VITTAL clinical trial (ClinicalTrials.gov number NCT02740608) outcomes, using normothermic machine perfusion (NMP) to objectively assess livers discarded by ...

Subject

Machine perfusion

Medicine

Transplantation

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