Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer’s Disease

Silva Dourado, Naiara; Dos Santos Souza, Cleide; Marylin Alves de Almeida, Monique; Bispo da Silva, Alessandra; Lino dos Santos, Balbino; Diógenes Amaral da Silva, Víctor; Martimbianco de Assis, Adriano; Souza da Silva, Jussemara; O. Souza, Diogo; de Fátima Dias Costa, Maria; M. Butt, Arthur; Lima Costa, Sílvia

doi:10.3389/fnagi.2020.00119

Public

Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer’s Disease

Published in Frontiers in Aging Neuroscience • May 15, 2020

Authors:

Naiara Silva Dourado

Cleide Dos Santos Souza

Monique Marylin Alves de Almeida

Abstract

Neurodegenerative disorders (ND) are characterized by the progressive and irreversible loss of neurons. Alzheimer’s Disease (AD) is the most incident age-related ND, in which presence of a chronic inflammatory compound seems to be related to its pathogenesis. Different stimuli in the central nervous...

Subject

Apigenin

Neuroprotection

Neuroinflammation

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