Modeling the Impact of Cardiopulmonary Irradiation on Overall Survival in NRG Oncology Trial RTOG 0617

Thor, Maria; O. Deasy, Joseph; Hu, Chen; Gore, Elizabeth; Bar‐Ad, Voichita; G. Robinson, Clifford; Wheatley, Matthew; Hun Oh, Jung; A. Bogart, Jeffrey; I. Garces, Yolanda; S. Kavadi, Vivek; Narayan, Samir; Iyengar, Puneeth; S. Witt, Jacob; W. Welsh, James; D. Koprowski, Cristopher; M. Larner, James; Xiao, Ying; D. Bradley, Jeffrey

doi:10.1158/1078-0432.ccr-19-2627

Public

Modeling the Impact of Cardiopulmonary Irradiation on Overall Survival in NRG Oncology Trial RTOG 0617

Published in Clinical Cancer Research • May 12, 2020

Authors:

Maria Thor

Joseph O. Deasy

Chen Hu

Abstract

Abstract Purpose: To quantitatively predict the impact of cardiopulmonary dose on overall survival (OS) after radiotherapy for locally advanced non–small cell lung cancer. Experimental Design: We used the NRG Oncology/RTOG 0617 dataset. The model building procedure was preregistered on a public webs...

Subject

Medicine

Proportional hazards model

Radiation therapy

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