Extracellular Vesicle–Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models

Yang, Li; Han, Bing; Zhang, Zhiting; Wang, Shuguo; Bai, Ying; Zhang, Yuan; Tang, Ying; Du, Lingli; Xu, Ling; Wu, Fangfang; Zuo, Lei; Chen, Xufeng; Lin, Yu; Liu, Kezhong; Ye, Qingqing; Chen, Biling; Li, Bin; Tang, Tianci; Wang, Yu; Shen, Ling; Wang, Guangtian; Ju, Minzi; Yuan, Mengqin; Jiang, Wei; H. Zhang, John; Hu, Gang; Wang, Jianhong; Yao, Honghong

doi:10.1161/circulationaha.120.045765

Public

Extracellular Vesicle–Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models

Published in Circulation • May 22, 2020

Authors:

Li Yang

Bing Han

Zhiting Zhang

Abstract

BACKGROUND: Stroke is a leading cause of adult disability that can severely compromise the quality of life of patients, yet no effective medication currently exists to accelerate rehabilitation. A variety of circular RNA (circRNA) molecules are known to function in ischemic brain injury. Lentivirus-...

Subject

Medicine

Stroke (engine)

Neuroplasticity

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!