ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens

Suo, Tao; Liu, Xinjin; Feng, Jiangpeng; Guo, Ming; Hu, Wenjia; Guo, Dong; Ullah, Hafiz; Yang, Yang; Zhang, Qiuhan; Wang, Xin; Sajid, Muhammad; Huang, Zhixiang; Deng, Liping; Chen, Tielong; Liu, Fang; Xu, Ke; Liu, Yuan; Qi, Zhang; Liu, Yingle; Xiong, Yong; Chen, Guozhong; Lan, Ke; Chen, Yu

doi:10.1080/22221751.2020.1772678

Public

ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens

Published in Emerging Microbes & Infections • Jan 1, 2020

Authors:

Tao Suo

Xinjin Liu

Jiangpeng Feng

Abstract

Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to the low viral load specimens and the limitations of RT-PCR, significant numbers of false negative reports are inevitable, which results in failure to timely diagnose, cut off...

Subject

Digital polymerase chain reaction

Medicine

Viral load

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