Urinary 8-OHdG as a Biomarker for Oxidative Stress: A Systematic Literature Review and Meta-Analysis

Graille, M.; Wild, Pascal; Sauvain, Jean‐Jacques; Hemmendinger, Maud; Guseva Canu, Irina; B. Hopf, Nancy

doi:10.3390/ijms21113743

Public

Urinary 8-OHdG as a Biomarker for Oxidative Stress: A Systematic Literature Review and Meta-Analysis

Published in International Journal of Molecular Sciences • May 26, 2020

Authors:

M. Graille

Pascal Wild

Jean‐Jacques Sauvain

Abstract

Oxidative stress reflects a disturbance in the balance between the production and accumulation of reactive oxygen species (ROS). ROS are scavenged by the antioxidant system, but when in excess concentration, they can oxidize proteins, lipids, and DNA. DNA damage is usually repaired, and the oxidized...

Subject

Interquartile range

Oxidative stress

Biomarker

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