Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA

Raduà, Joaquim; Vieta, Eduard; T. Shinohara, Russell; Kochunov, Peter; Quidé, Yann; J. Green, Melissa; Shannon Weickert, Cynthia; W. Weickert, Thomas; Bruggemann, Jason; Kircher, Tilo; Nenadić, Igor; J. Cairns, Murray; L. Seal, Marc; Schall, Ulrich; Henskens, Frans; M. Fullerton, Janice; Mowry, Bryan; Pantelis, Christos; Lenroot, Rhoshel; Cropley, Vanessa; M. Loughland, Carmel; J. Scott, Rodney; H. Wolf, Daniel; D. Satterthwaite, Theodore; Tan, Yunlong; Sim, Kang; Piras, Fabrizio; Spalletta, Gianfranco; Banaj, Nerisa; Pomarol‐Clotet, Edith; Solanes, Aleix; Albajes‐Eizagirre, Anton; J. Canales‐Rodríguez, Erick; Sarró, Salvador; Di Giorgio, Annabella; Bertolino, Alessandro; Stäblein, Michael; Oertel, Viola; Knöchel, Christian; Borgwardt, Stefan; S. du Plessis, Stefan; Yun, Je‐Yeon; Soo Kwon, Jun; Dannlowski, Udo; Hahn, Tim; Grotegerd, Dominik; Alloza, Clara; Arango, Celso; Janssen, Joost; M. Díaz‐Caneja, Covadonga; Jiang, Wenhao; D. Calhoun, Vince; Ehrlich, Stefan; Yang, Kun; G. Cascella, Nicola; Takayanagi, Yoichiro; Sawa, Akira; S. Tomyshev, A.; С. Лебедева, И.; Г. Каледа, В.; Kirschner, Matthias; Höschl, Cyril; Tomeček, David; Škoch, Antonín; van Amelsvoort, Thérèse; Bakker, Geor; James, Anthony; Preda, Adrian; Weideman, Andrea; J. Stein, Dan; M. Howells, Fleur; Uhlmann, Anne; Temmingh, Henk; López‐Jaramillo, Carlos; M. Díaz‐Zuluaga, Ana; Fortea, Lydia; Martínez‐Heras, Eloy; Solana, Elisabeth; Llufriú, Sara; Jahanshad, Neda; M. Thompson, Paul; A. Turner, Jessica; G.M. van Erp, Theo; C. Glahn, David; D. Pearlson, Godfrey; Hong, Elliot; Krug, Axel; J. Carr, Vaughan; A. Tooney, Paul; Cooper, Gavin; E. Rasser, Paul; T. Michie, Patricia; V. Catts, Stanley; E. Gur, Raquel; C. Gur, Ruben; Yang, Fude; Fan, Fengmei; Chen, Jingxu; Guo, Hua; Tan, Shuping; Wang, Zhiren; Xiang, Hong; Piras, Federica; Assogna, Francesca; Salvador, Raymond; J. McKenna, Peter; Bonvino, Aurora; King, Margaret; Kaiser, Stefan; Nguyen, Dana; A. Pineda‐Zapata, Julian

doi:10.1016/j.neuroimage.2020.116956

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Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA

Published in NeuroImage • May 26, 2020

Authors:

Joaquim Raduà

Eduard Vieta

Russell T. Shinohara

Abstract

A common limitation of neuroimaging studies is their small sample sizes. To overcome this hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium combines neuroimaging data from many institutions worldwide. However, this introduces heterogeneity due to different scanni...

Subject

Statistical power

Neuroimaging

Meta-analysis

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