Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients

d'Aldebert, Emilie; Quaranta, Muriel; Sébert, Morgane; Bonnet, Delphine; Kirzin, Sylvain; Portier, G.; Duffas, Jean‐Pierre; Chabot, Sophie; Lluel, Philippe; Allart, Sophie; Ferrand, Audrey; Alric, Laurent; Racaud‐Sultan, Claire; Mas, Emmanuel; Deraison, Céline; Vergnolle, Nathalie

doi:10.3389/fcell.2020.00363

Public

Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients

Published in Frontiers in Cell and Developmental Biology • Jun 4, 2020

Authors:

Emilie d'Aldebert

Muriel Quaranta

Morgane Sébert

Abstract

Inflammatory Bowel Diseases (IBD) are chronic inflammatory disorders, where epithelial defects drive, at least in part, some of the pathology. We reconstituted human intestinal epithelial organ, by using three-dimension culture of human colon organoids. Our aim was to characterize morphological and ...

Subject

Organoid

Inflammatory bowel disease

Phenotype

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