Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

J. M. Brouwer, Philip; G. Caniels, Tom; van der Straten, Karlijn; L. Snitselaar, Jonne; Aldon, Yoann; Bangaru, Sandhya; L. Torres, Jonathan; M.A. Okba, Nisreen; Claireaux, Mathieu; Kerster, Gius; E. H. Bentlage, Arthur; M. van Haaren, Marlies; Guerra, Denise; A. Burger, Judith; E. Schermer, Edith; D. Verheul, Kirsten; van der Velde, Niels; van der Kooi, Alex; van Schooten, Jelle; J. van Breemen, Mariëlle; P. L. Bijl, Tom; Sliepen, Kwinten; Aartse, Aafke; Derking, Ronald; Bontjer, Ilja; A. Kootstra, Neeltje; Joost Wiersinga, W.; Vidarsson, Gestur; L. Haagmans, Bart; B. Ward, Andrew; J. de Bree, Godelieve; W. Sanders, Rogier; J. van Gils, Marit

doi:10.1126/science.abc5902

Public

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

Published in Science • Jun 15, 2020

Authors:

Philip J. M. Brouwer

Tom G. Caniels

Karlijn van der Straten

Abstract

The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a large impact on global health, travel, and economy. Therefore, preventative and therapeutic measures are urgently needed. Here, we isolated monoclonal antibodies from three convalescent coronavirus disease 201...

Subject

Coronavirus disease 2019 (COVID-19)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

2019-20 coronavirus outbreak

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