Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

F. Rogers, Thomas; Zhao, Fangzhu; Huang, Deli; Beutler, Nathan; Burns, Alison; He, Wan-ting; Limbo, Oliver; Smith, Chloe; Song, Ge; Woehl, Jordan; Yang, Linlin; K. Abbott, Robert; Callaghan, Sean; Garcia, Elijah; Hurtado, Jonathan; Parren, Mara; Peng, Linghang; Ramirez, Sydney; Ricketts, James; J. Ricciardi, Michael; A. Rawlings, Stephen; C. Wu, Nicholas; Yuan, Meng; M. Smith, Davey; Nemazee, David; R. Teijaro, John; E. Voss, James; A. Wilson, Ian; Andrabi, Raiees; Briney, Bryan; Landais, Elise; Sok, Devin; G. Jardine, Joseph; R. Burton, Dennis

doi:10.1126/science.abc7520

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Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

Shared by NobleBlocks on Aug 21, 2020 • 12:00 AM UTC

Authors:

Thomas F. Rogers

Fangzhu Zhao

Deli Huang

Abstract

Protective neutralizing antibodies Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neutralizing antibodies, which confer strong protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ...

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