Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses in Drosophila melanogaster

C. Lecheta, Melise; N. Awde, David; S. O’Leary, Thomas; N. Unfried, Laura; A. Jacobs, Nicholas; H. Whitlock, Miles; McCabe, Eleanor; Powers, Beck; Bora, Katie; S. Waters, James; J. Axen, Heather; Frietze, Seth; L. Lockwood, Brent; M. Teets, Nicholas; Helms Cahan, Sara

doi:10.3389/fgene.2020.00658

Public

Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses in Drosophila melanogaster

Published in Frontiers in Genetics • Jun 23, 2020

Authors:

Melise C. Lecheta

David N. Awde

Thomas S. O’Leary

Abstract

Thermal tolerance of an organism depends on both the ability to dynamically adjust to a thermal stress and preparatory developmental processes that enhance thermal resistance. However, the extent to which standing genetic variation in thermal tolerance alleles influence dynamic stress responses vs. ...

Subject

Genome-wide association study

Drosophila melanogaster

Biology

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