High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study

Talvitie, Eva‐Maria; Vilhonen, Heikki; Kurki, Samu; Karlsson, Antti; Orte, Katri; Almangush, Alhadi; Mohamed, Hesham; Liljeroos, Lassi; Singh, Yajuvinder; Leivo, Ilmo; Laitinen, Tarja; Kallajoki, Markku; Taimen, Pekka

doi:10.1016/j.neo.2020.05.004

Public

High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study

Published in Neoplasia • Jun 22, 2020

Authors:

Eva‐Maria Talvitie

Heikki Vilhonen

Samu Kurki

Abstract

OBJECTIVES: Tumor mutation burden (TMB) is an emerging predictive cancer biomarker. Few studies have addressed the prognostic role of TMB in non-small cell lung carcinoma, with conflicting results. Moreover, the association of TMB with different histological subtypes of lung adenocarcinoma has hithe...

Subject

Adenocarcinoma

Medicine

Oncology

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