cGAS-STING, an important pathway in cancer immunotherapy

Jiang, Minlin; Chen, Peixin; Wang, Lei; Li, Wei; Chen, Bin; Liu, Yu; Wang, Hao; Zhao, Sha; Ye, Lingyun; He, Yayi; Zhou, Caicun

doi:10.1186/s13045-020-00916-z

Public

cGAS-STING, an important pathway in cancer immunotherapy

Published in Journal of Hematology & Oncology • Jun 22, 2020

Authors:

Minlin Jiang

Peixin Chen

Lei Wang

Abstract

Cytosolic DNA sensing, the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, is an important novel role in the immune system. Multiple STING agonists were developed for cancer therapy study with great results achieved in pre-clinical work. Recent progress in the mechanical...

Subject

Sting

Hematology

Medicine

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