Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's <i>continuum</i>

Milà‐Alomà, Marta; Salvadó, Gemma; Domingo Gispert, Juan; Vilor‐Tejedor, Natalia; Grau‐Rivera, Oriol; Sala‐Vila, Aleix; Sánchez‐Benavides, Gonzalo; M. Arenaza‐Urquijo, Eider; Crous‐Bou, Marta; Maria González‐de‐Echávarri, José; Minguillon, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez‐Calvet, Marc; Luis Molinuevo, José; the ALFA study, for

doi:10.1002/alz.12131

Public

Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

Shared by NobleBlocks on Jun 23, 2020 • 12:00 AM UTC

Authors:

Marta Milà‐Alomà

Gemma Salvadó

Juan Domingo Gispert

Abstract

Abstract Introduction The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. Methods We used NeuroToolKit and Elecsys ® immunoassays to measure cerebrospinal fluid (CSF) amyloid‐β (Aβ)42, Aβ40, phosphorylated tau (p‐tau), total tau (t‐tau), ne...

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