Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

Milà‐Alomà, Marta; Salvadó, Gemma; Domingo Gispert, Juan; Vilor‐Tejedor, Natàlia; Grau‐Rivera, Oriol; Sala‐Vila, Aleix; Sánchez‐Benavides, Gonzalo; M. Arenaza‐Urquijo, Eider; Crous‐Bou, Marta; María Gónzalez‐de‐Echávarri, José; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez‐Calvet, Marc; Luís Molinuevo, José; the ALFA study, for

doi:10.1002/alz.12131

Public

Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

Published in Alzheimer s & Dementia • Jun 23, 2020

Authors:

Marta Milà‐Alomà

Gemma Salvadó

Juan Domingo Gispert

Abstract

INTRODUCTION: The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. METHODS: immunoassays to measure cerebrospinal fluid (CSF) amyloid-β (Aβ)42, Aβ40, phosphorylated tau (p-tau), total tau (t-tau), neurofilament light (NfL), neurogranin, sTRE...

Subject

Neurogranin

Neurodegeneration

Cerebrospinal fluid

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