Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

Fortea, Juan; Vilaplana, Eduard; Carmona‐Iragui, María; Benejam, Bessy; Videla, Laura; Barroeta, Isabel; Fernández, Susana; Altuna, Miren; Pegueroles, Jordi; Montal, Víctor; Valldeneu, Sílvia; Giménez, Sandra; González‐Ortiz, Sofía; Muñoz, Laia; Estellés, Teresa; Illán‐Gala, Ignacio; Belbin, Olivia; Camacho, Valle; R. Wilson, Liam; Annus, Tiina; S. Osorio, Ricardo; Videla, Sebastián; Lehmann, Sylvain; Holland, Anthony; Alcolea, Daniel; Clarimón, Jordi; Zaman, Shahid; Blesa, Rafael; Lleó, Alberto

doi:10.1016/s0140-6736(20)30689-9

Public

Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

Published in The Lancet • Jun 1, 2020

Authors:

Juan Fortea

Eduard Vilaplana

María Carmona‐Iragui

Abstract

BackgroundAlzheimer's disease and its complications are the leading cause of death in adults with Down syndrome. Studies have assessed Alzheimer's disease in individuals with Down syndrome, but the natural history of biomarker changes in Down syndrome has not been established. We characterised the o...

Subject

Biomarker

Down syndrome

Medicine

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