Effects of Allopurinol on the Progression of Chronic Kidney Disease

V. Badve, Sunil; M. Pascoe, Elaine; Tiku, Anushree; Boudville, Neil; G. Brown, Fiona; Cass, Alan; Clarke, Philip; Dalbeth, Nicola; O. Day, Richard; de Zoysa, Janak; Douglas, Bettina; Faull, Randall; C.H. Harris, David; M. Hawley, Carmel; Jones, Graham; Kanellis, John; C. Palmer, Suetonia; Perkovic, Vlado; K. Rangan, Gopala; Reidlinger, Donna; Robison, Laura; Walker, Robert; Walters, Giles; W. Johnson, David

doi:10.1056/nejmoa1915833

Public

Effects of Allopurinol on the Progression of Chronic Kidney Disease

Published in New England Journal of Medicine • Jun 24, 2020

Authors:

Sunil V. Badve

Elaine M. Pascoe

Anushree Tiku

Abstract

BACKGROUND: Elevated serum urate levels are associated with progression of chronic kidney disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease who are at risk for progression is...

Subject

Allopurinol

Medicine

Kidney disease

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