Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma

Feng, Jiao; Li, Jingjing; Wu, Liwei; Yu, Qiang; Ji, Jie; Wu, Jianye; Dai, Weiqi; Guo, Chuanyong

doi:10.1186/s13046-020-01629-4

Public

Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma

Published in Journal of Experimental & Clinical Cancer Research • Jul 6, 2020

Authors:

Jiao Feng

Jingjing Li

Liwei Wu

Abstract

Liver cancer has become the sixth most diagnosed cancer and the fourth leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible for up to 75-85% of primary liver cancers, and sorafenib is the first targeted drug for advanced HCC treatment. However, sorafenib resistance ...

Subject

Hepatocellular carcinoma

Glycolysis

Anaerobic glycolysis

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