Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer

Radovich, Milan; Jiang, Guanglong; A. Hancock, Bradley; R. Chitambar, Christopher; Nanda, Rita; I. Falkson, Carla; Lynce, Filipa; Gallagher, Christopher; Isaacs, Claudine; Blaya, Marcelo; Paplomata, Elisavet; Walling, Radhika; Daily, Karen; Mahtani, Reshma; A. Thompson, Michael; Graham, Robert; E. Cooper, Maureen; C. Pavlick, Dean; A. Albacker, Lee; P. Gregg, Jeffrey; P. Solzak, Jeffrey; Chen, Yu-Hsiang; Bales, Casey; Cantor, Erica; Shen, Fei; Maria Storniolo, Anna; Badve, Sunil; J. Ballinger, Tarah; Chang, Chun-Li; Yuan, Žhong; A. Savran, Cagri; D. Miller, Kathy; P. Schneider, Bryan

doi:10.1001/jamaoncol.2020.2295

Public

Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer

Published in JAMA Oncology • Jul 9, 2020

Authors:

Milan Radovich

Guanglong Jiang

Bradley A. Hancock

Abstract

Importance: A significant proportion of patients with early-stage triple-negative breast cancer (TNBC) are treated with neoadjuvant chemotherapy. Sequencing of circulating tumor DNA (ctDNA) after surgery, along with enumeration of circulating tumor cells (CTCs), may be used to detect minimal residua...

Subject

Medicine

Oncology

Circulating tumor cell

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!