m<sup>6</sup>A modification-mediated BATF2 acts as a tumor suppressor in gastric cancer through inhibition of ERK signaling.

JW, Xie; XB, Huang; QY, Chen; YB, Ma; YJ, Zhao; LC, Liu; JB, Wang; JX, Lin; J, Lu; LL, Cao; M, Lin; RH, Tu; CH, Zheng; CM, Huang; P, Li

doi:10.1186/s12943-020-01223-4

Public

m6A modification-mediated BATF2 acts as a tumor suppressor in gastric cancer through inhibition of ERK signaling.

Shared by NobleBlocks on Jul 10, 2020 • 12:00 AM UTC

Authors:

Xie JW

Huang XB

Chen QY

Abstract

Background BATF2, also known as SARI, has been implicated in tumor progression. However, its role, underlying mechanisms, and prognostic significance in human gastric cancer (GC) are elusive.Methods We obtained GC tissues and corresponding normal tissues from 8 patients and identified BATF2 as a dow...

Subject

p53

Gastric cancer

ERK

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