Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

M Folegatti, Pedro; J Ewer, Katie; K Aley, Parvinder; Angus, Brian; Becker, Stephan; Belij-Rammerstorfer, Sandra; Bellamy, Duncan; Bibi, Sagida; Bittaye, Mustapha; A Clutterbuck, Elizabeth; Dold, Christina; N Faust, Saul; Finn, Adam; L Flaxman, Amy; Hallis, Bassam; Heath, Paul; Jenkin, Daniel; Lazarus, Rajeka; Makinson, Rebecca; M Minassian, Angela; M Pollock, Katrina; Ramasamy, Maheshi; Robinson, Hannah; Snape, Matthew; Tarrant, Richard; Voysey, Merryn; Green, Catherine; D Douglas, Alexander; V S Hill, Adrian; Lambe, Teresa; C Gilbert, Sarah; J Pollard, Andrew; Aboagye, Jeremy; Adams, Kelly; Ali, Aabidah; Allen, Elizabeth; L. Allison, Jennifer; Anslow, Rachel; H. Arbe-Barnes, Edward; Babbage, Gavin; Baillie, Kenneth; Baker, Megan; Baker, Natalie; Baker, Philip; Baleanu, Ioana; Ballaminut, Juliana; Barnes, Eleanor; Barrett, Jordan; Bates, Louise; Batten, Alexander; Beadon, Kirsten; Beckley, Rebecca; Berrie, Eleanor; Berry, Lisa; Beveridge, Amy; R. Bewley, Kevin; Margreet Bijker, Else; Bingham, Tracey; Blackwell, Luke; L. Blundell, Caitlin; Bolam, Emma; Boland, Elena; Borthwick, Nicola; Bower, Thomas; Boyd, Amy; Brenner, Tanja; D. Bright, Philip; Brown-O'Sullivan, Charlie; Brunt, Emily; Burbage, Jamie; Burge, Sharon; R. Buttigieg, Karen; Byard, Nicholas; Cabera Puig, Ingrid; Calvert, Anna; Camara, Susana; Cao, Michelangelo; Cappuccini, Federica; Carr, Melanie; W. Carroll, Miles; Carter, Victoria; Cathie, Katrina; J. Challis, Ruth; Charlton, Sue; Chelysheva, Irina; Cho, Jee-Sun; Cicconi, Paola; Cifuentes, Liliana; Clark, Helen; Clark, Elizabeth; Cole, Tom; Colin-Jones, Rachel; P. Conlon, Christopher; Cook, Aislinn; S. Coombes, Naomi; Cooper, Rachel; A. Cosgrove, Catherine; Coy, Karen; E.M. Crocker, Wendy; J. Cunningham, Christina; E. Damratoski, Brad; Dando, Lynne; S. Datoo, Mehreen; Davies, Hannah; De Graaf, Hans; Demissie, Tesfaye; Di Maso, Claudio; Dietrich, Isabelle; Dong, Tao; R. Donnellan, Francesca; Douglas, Naomi; Downing, Charlotte; Drake, Jonathan; Drake-Brockman, Rachael; Elizabeth Drury, Ruth; Jane Dunachie, Susanna; J. Edwards, Nick; D.L. Edwards, Frances; J. Edwards, Chris; C. Elias, Sean; J. Elmore, Michael; R.W. Emary, Katherine; Rex English, Marcus; Fagerbrink, Susanne; Felle, Sally; Feng, Shuo; Field, Samantha; Fixmer, Carine; Fletcher, Clare; J. Ford, Karen; Fowler, Jamie; Fox, Polly; Francis, Emma; Frater, John; Furze, Julie; Fuskova, Michelle; Galiza, Eva; Gbesemete, Diane; Gilbride, Ciaran; Godwin, Kerry; Gorini, Giacomo; Goulston, Lyndsey; Grabau, Caroline; Gracie, Lara; Gray, Zoe; Belle Guthrie, Lucy; Hackett, Mark; Halwe, Sandro; Hamilton, Elizabeth; Hamlyn, Joseph; Hanumunthadu, Brama; Harding, Irasha; A. Harris, Stephanie; Harris, Andrew; Harrison, Daisy; Harrison, Clare; C. Hart, Thomas; Haskell, Louise; Hawkins, Sophia; Head, Ian; Aaron Henry, John; Hill, Jennifer; H.C. Hodgson, Susanne; M. Hou, Mimi; Howe, Elizabeth; Howell, Nicola; Hutlin, Cecilia; Ikram, Sabina; Isitt, Catherine; Iveson, Poppy; Jackson, Susan; Jackson, Frederic; William James, Sir; Jenkins, Megan; Jones, Elizabeth; Jones, Kathryn; E. Jones, Christine; Jones, Bryony; Kailath, Reshma; Karampatsas, Konstantinos; Keen, Jade; Kelly, Sarah; Kelly, Dearbhla; Kerr, David; Kerridge, Simon; Khan, Liaquat; Khan, Uzma; Killen, Annabel; Kinch, Jasmin; B. King, Thomas; King, Lloyd; King, Jade; Kingham-Page, Lucy; Klenerman, Paul; Knapper, Francesca; C. Knight, Julian; Knott, Daniel; Koleva, Stanislava; Kupke, Alexandra; W. Larkworthy, Colin

doi:10.1016/s0140-6736(20)31604-4

Public

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

Shared by NobleBlocks on Aug 1, 2020 • 12:00 AM UTC

Authors:

Pedro M Folegatti

Katie J Ewer

Parvinder K Aley

Research Assistant

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