Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

E. Remy, Kenneth; Mazer, Monty; A. Striker, David; H. Ellebedy, Ali; H. Walton, Andrew; Unsinger, Jacqueline; M. Blood, Teresa; A. Mudd, Philip; J. Yi, Daehan; A. Mannion, Daniel; F. Osborne, Dale; Scott Martin, R.; J. Anand, Nitin; P. Bosanquet, James; Blood, Jane; M. Drewry, Anne; C. Caldwell, Charles; R. Turnbull, Isaiah; C. Brakenridge, Scott; L. Moldwawer, Lyle; S. Hotchkiss, Richard

doi:10.1172/jci.insight.140329

Public

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

Shared by NobleBlocks on Sep 3, 2020 • 12:00 AM UTC

Authors:

Kenneth E. Remy

Monty Mazer

David A. Striker

Abstract

COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained viral dissemination and organ injury. A key explanation ...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!