METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications.

D, Jian; Y, Wang; L, Jian; H, Tang; L, Rao; K, Chen; Z, Jia; W, Zhang; Y, Liu; X, Chen; X, Shen; C, Gao; S, Wang; M, Li

doi:10.7150/thno.45178

Public

METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications.

Shared by NobleBlocks on Jul 11, 2020 • 12:00 AM UTC

Authors:

Jian D

Wang Y

Jian L

Abstract

Aims: The N6-methyladenosine (m6A) modification plays an important role in various biological processes, but its role in atherosclerosis remains unknown. The aim of this study was to investigate the role and mechanism of m6A modification in endothelial cell inflammation and its influence on atherosc...

Subject

Atherosclerosis

Foxo1

Endothelial Inflammation

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