Long-lasting severe immune dysfunction in Ebola virus disease survivors

Wiedemann, Aurélie; Foucat, Emile; Hocini, Hakim; Lefebvre, Cécile; P. Hejblum, Boris; Durand, Mélany; Krüger, Miriam; Kabinet Kéita, Alpha; Ayouba, Ahidjo; Mély, Stéphane; Fernandez, José-Carlos; Touré, Abdoulaye; Fourati, Slim; Lévy‐Marchal, Claire; Raoul, Hervé; Delaporte, Éric; Koivogui, Lamine; Thiébaut, Rodolphe; Lacabaratz, Christine; Lévy, Yves; Lévy, Yves; Study Group, PostEboGui; Ayouba, Ahidjo; Delaporte, Eric; Kabinet Keita, Alpha; Koivogui, Lamine; Lacabaratz, Christine; Lévy, Yves; Levy, Yves; Levy, Yves; Raoul, Hervé; Touré, Abdoulaye

doi:10.1038/s41467-020-17489-7

Public

Long-lasting severe immune dysfunction in Ebola virus disease survivors

Published in Nature Communications • Jul 24, 2020

Authors:

Aurélie Wiedemann

Emile Foucat

Hakim Hocini

Abstract

Long-term follow up studies from Ebola virus disease (EVD) survivors (EBOV_S) are lacking. Here, we evaluate immune and gene expression profiles in 35 Guinean EBOV_S from the last West African outbreak, a median of 23 months (IQR [18-25]) after discharge from treatment center. Compared with healthy ...

Subject

Ebola virus

Immune system

Virology

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