Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody

Lv, Zhe; Deng, Yong‐Qiang; Ye, Qing; Cao, Lei; Sun, Chun-Yun; Fan, Changfa; Huang, Weijin; Sun, Shihui; Sun, Yao; Zhu, Ling; Chen, Qi; Wang, Nan; Nie, Jianhui; Cui, Zhen; Zhu, Dandan; Shaw, Neil; Li, Xiao-Feng; Li, Qianqian; Xie, Liangzhi; Wang, Youchun; Rao, Zihe; Qin, Cheng‐Feng; Wang, Xiangxi

doi:10.1126/science.abc5881

Public

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody

Published in Science • Jul 23, 2020

Authors:

Zhe Lv

Yong‐Qiang Deng

Qing Ye

Abstract

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are no approved vaccines or therapeutics for treating COVID-19. Here we report a humanized monoclonal antibody, H014, t...

Subject

Neutralization

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Virology

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