Multi-Omics Characterization of the 4T1 Murine Mammary Gland Tumor Model

Schrörs, Barbara; Boegel, Sebastian; Albrecht, Christian; Bukur, Thomas; Bukur, Valesca; Holtsträter, Christoph; Ritzel, Christoph; Manninen, Katja; D. Tadmor, Arbel; Vormehr, Mathias; Şahin, Uğur; Löwer, Martin

doi:10.3389/fonc.2020.01195

Public

Multi-Omics Characterization of the 4T1 Murine Mammary Gland Tumor Model

Published in Frontiers in Oncology • Jul 23, 2020

Authors:

Barbara Schrörs

Sebastian Boegel

Christian Albrecht

Abstract

Background Tumor models are critical for our understanding of cancer and the development of cancer therapeutics. The 4T1 murine mammary cancer cell line is one of the most widely used breast cancer models. Here, we present an integrated map of the genome, transcriptome and immunome of 4T1. Results W...

Subject

Biology

Cancer

Cancer research

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