Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva, Laura; Yuan, Shuofeng; Yin, Xin; Martin‐Sancho, Laura; Matsunaga, Naoko; Pache, Lars; Burgstaller-Muehlbacher, Sebastian; D. De Jesus, Paul; Teriete, Peter; Hull, Mitchell; W. Chang, Max; Fuk‐Woo Chan, Jasper; Cao, Jianli; Kwok‐Man Poon, Vincent; M. Herbert, Kristina; Cheng, Kuoyuan; H. Nguyen, Tu-Trinh; Rubanov, Andrey; Pu, Yuan; Nguyen, Courtney; Choi, Angela; Rathnasinghe, Raveen; Schotsaert, Michael; Miorin, Lisa; Déjosez, Marion; P. Zwaka, Thomas; Sit, Ko‐Yung; Martínez‐Sobrido, Luis; Liu, Wen‐Chun; M. White, Kris; E. Chapman, Mackenzie; K. Lendy, Emma; Glynne, Richard; A. Albrecht, Randy; Ruppin, Eytan; D. Mesecar, Andrew; R. Johnson, Jeffrey; Benner, Christopher; Sun, Ren; G. Schultz, Peter; I. Su, Andrew; García‐Sastre, Adolfo; K. Chatterjee, Arnab; Yuen, Kwok‐Yung; K. Chanda, Sumit

doi:10.1038/s41586-020-2577-1

Public

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Published in Nature • Jul 24, 2020

Authors:

Laura Riva

Shuofeng Yuan

Xin Yin

Abstract

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 has triggered an ongoing global pandemic of the severe pneumonia-like disease coronavirus disease 2019 (COVID-19)1. The development of a vaccine is likely to take at least 12–18 months, and the typical timeline for...

Subject

Drug repositioning

Repurposing

Medicine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!