Interplay between SARS-CoV-2 and the type I interferon response

Sá Ribeiro, Margarida; Jouvenet, Nolwenn; Dreux, Marlène; Nisole, Sébastien

doi:10.1371/journal.ppat.1008737

Public

Interplay between SARS-CoV-2 and the type I interferon response

Published in PLoS Pathogens • Jul 29, 2020

Authors:

Margarida Sá Ribeiro

Nolwenn Jouvenet

Marlène Dreux

Abstract

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. An unbalanced immune response, characterized by a weak production of type I interferons (IFN-Is) and an exacerbated release of proinflammatory cytokines, contributes to the severe forms...

Subject

Interferon

Middle East respiratory syndrome coronavirus

Immunology

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