Functional annotation of human long noncoding RNAs via molecular phenotyping

A. Ramilowski, Jordan; Wai Yip, Chi; Agrawal, Saumya; Chang, Jen-Chien; Ciani, Yari; V. Kulakovskiy, Ivan; Mendez, Mickaël; Li Ching Ooi, Jasmine; F. Ouyang, John; Parkinson, Nick; Petri, Andreas; Roos, Leonie; Severin, Jessica; Yasuzawa, Kayoko; Abugessaisa, Imad; Akalin, Altuna; Antonov, Ivan; Arner, Erik; Bonetti, Alessandro; Bono, Hidemasa; Borsari, Beatrice; Brombacher, Frank; J. F. Cameron, Christopher; Vittorio Cannistraci, Carlo; Cardenas, Ryan; Cardon, Mélissa; Y. Chang, Howard; Dostie, Josée; Ducoli, Luca; V. Favorov, Alexander; Fort, Alexandre; Garrido-Martín, Diego; Gil, Noa; Gimenez, Juliette; Guler, Reto; Handoko, Lusy; Harshbarger, Jayson; Hasegawa, Akira; Hasegawa, Yuki; Hashimoto, Kosuke; Hayatsu, Norihito; Heutink, Peter; Hirose, Tetsuro; L. Imada, Eddie; Itoh, Masayoshi; Kaczkowski, Bogumił; Kanhere, Aditi; Kawabata, Emily; Kawaji, Hideya; Kawashima, Tsugumi; Thomas Kelly, S.; Kojima, Miki; Kondo, Naoto; Koseki, Haruhiko; Kouno, Tsukasa; Kratz, Anton; Kurowska‐Stolarska, Mariola; Tae-Jun Kwon, Andrew; T. Leek, Jeffrey; Lennartsson, Andreas; Lizio, Marina; Martínez López, Fernando; Luginbühl, Joachim; Maeda, Shiori; J. Makeev, Vsevolod; Marchionni, Luigi; A. Medvedeva, Yulia; Minoda, Aki; Müller, Ferenc; Muñoz-Aguirre, Manuel; Murata, Mitsuyoshi; Nishiyori, Hiromi; R. Nitta, Kazuhiro; Noguchi, Shuhei; Noro, Yukihiko; Nurtdinov, Ramil; Okazaki, Yasushi; Orlando, Valerio; Paquette, Denis; Parr, Callum; J. L. Rackham, Owen; Rizzu, Patrizia; F. Sánchez, Diego; Sandelin, Albin; Pillay, Sanjana; A. Semple, Colin; Shibayama, Youtaro; M. Sivaraman, Divya; Suzuki, Takahiro; C. Szumowski, Suzannah; Tagami, Michihira; S. Taylor, Martin; Terao, Chikashi; Thodberg, Malte; Thongjuea, Supat; Tripathi, Vidisha; Ulitsky, Igor; Verardo, Roberto; E. Vorontsov, Ilya; Yamamoto, Chinatsu; S. Young, Robert; Kenneth Baillie, J.; R. R. Forrest, Alistair; Guigó, Roderic; M. Hoffman, Michael; Hon, Chung-Chau; Kasukawa, Takeya; Kauppinen, Sakari; Kere, Juha; Lenhard, Boris; Schneider, Claudio; Suzuki, Harukazu; Yagi, Ken; de Hoon, Michiel; W. Shin, Jay; Carninci, Piero

doi:10.1101/gr.254219.119

Public

Functional annotation of human long noncoding RNAs via molecular phenotyping

Published in Genome Research • Jul 1, 2020

Authors:

Jordan A. Ramilowski

Chi Wai Yip

Saumya Agrawal

Abstract

Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down the expression of 285 lncRNAs in human dermal fibroblasts and quantified cellular growth, mor...

Subject

Biology

Computational biology

Long non-coding RNA

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