Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

Palmqvist, Sebastian; Janelidze, Shorena; T. Quiroz, Yakeel; Zetterberg, Henrik; Lopera, Francisco; Stomrud, Erik; Su, Yi; Chen, Yinghua; E. Serrano, Geidy; Leuzy, Antoine; Mattsson, Niklas; Strandberg, Olof; Smith, Ruben; Villegas, Andrés; Sepúlveda‐Falla, Diego; Chai, Xiyun; K. Proctor, Nicholas; G. Beach, Thomas; Blennow, Kaj; L. Dage, Jeffrey; M. Reiman, Eric; Hansson, Oskar

doi:10.1001/jama.2020.12134

Public

Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

Published in JAMA • Jul 28, 2020

Authors:

Sebastian Palmqvist

Shorena Janelidze

Yakeel T. Quiroz

Abstract

Importance: There are limitations in current diagnostic testing approaches for Alzheimer disease (AD). Objective: To examine plasma tau phosphorylated at threonine 217 (P-tau217) as a diagnostic biomarker for AD. Design, Setting, and Participants: Three cross-sectional cohorts: an Arizona-based neur...

Subject

Cohort

Medicine

Internal medicine

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