A large-scale binding and functional map of human RNA-binding proteins

L. Van Nostrand, Eric; Freese, Peter; Pratt, Henry; Wang, Xiaofeng; Wei, Xintao; Xiao, Rui; M. Blue, Steven; Chen, Jiayu; Cody, Neal; Domínguez, Daniel; Olson, Sara; Sundararaman, Balaji; Zhan, Lijun; Bazile, Cassandra; Philip Benoit Bouvrette, Louis; Bergalet, Julie; O. Duff, Michael; E. Garcia, Keri; Gelboin-Burkhart, Chelsea; Hochman, Myles; Lambert, Nicole; Li, Hairi; P. McGurk, Michael; B. Nguyen, Thai; Palden, Tsultrim; Rabano, Ines; Sathe, Shashank; Stanton, Rebecca; Su, Amanda; Wang, Ruth; A. Yee, Brian; Zhou, Bing; L. Louie, Ashley; Aigner, Stefan; Fu, Xiang‐Dong; Lécuyer, Éric; B. Burge, Christopher; R. Graveley, Brenton; Yeo, G

doi:10.1038/s41586-020-2077-3

Public

A large-scale binding and functional map of human RNA-binding proteins

Published in Nature • Jul 29, 2020

Authors:

Eric L. Van Nostrand

Peter Freese

Henry Pratt

Abstract

. Here we introduce a new data set of RNA elements in the human genome that are recognized by RNA-binding proteins (RBPs), generated as part of the Encyclopedia of DNA Elements (ENCODE) project phase III. This class of regulatory elements functions only when transcribed into RNA, as they serve as th...

Subject

RNA-binding protein

RNA

Biology

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