Intracoronary ALLogeneic heart STem cells to Achieve myocardial Regeneration (ALLSTAR): a randomized, placebo-controlled, double-blinded trial

Makkar, Raj; J. Kereiakes, Dean; Aguirre, Frank; J. Kowalchuk, Glen; Chakravarty, Tarun; Malliaras, Konstantinos; S. Francis, Gary; J. Povsic, Thomas; A. Schatz, Richard; H. Traverse, Jay; M. Pogoda, Janice; Smith, Rachel; Marbán, Linda; D. Ascheim, Deborah; R. Ostovaneh, Mohammad; A.C. Lima, João; N. DeMaria, Anthony; Marbán, Eduardo; D. Henry, Timothy

doi:10.1093/eurheartj/ehaa541

Public

Intracoronary ALLogeneic heart STem cells to Achieve myocardial Regeneration (ALLSTAR): a randomized, placebo-controlled, double-blinded trial

Published in European Heart Journal • Jun 25, 2020

Authors:

Raj Makkar

Dean J. Kereiakes

Frank Aguirre

Abstract

AIMS: Cardiosphere-derived cells (CDCs) are cardiac progenitor cells that exhibit disease-modifying bioactivity in various models of cardiomyopathy and in previous clinical studies of acute myocardial infarction (MI), dilated cardiomyopathy, and Duchenne muscular dystrophy. The aim of the study was ...

Subject

Medicine

Ejection fraction

Cardiology

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