Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

Mateus, José; Grifoni, Alba; Tarke, Alison; Sidney, John; I. Ramirez, Sydney; M. Dan, Jennifer; C. Burger, Zoe; A. Rawlings, Stephen; M. Smith, Davey; J. Phillips, Elizabeth; Mallal, S.; Lammers, Marshall; Rubiro, Paul; Quiambao, Lorenzo; Sutherland, Aaron; Dawen Yu, Esther; da Silva Antunes, Ricardo; Greenbaum, Jason; Frazier, April; J. Markmann, Alena; Premkumar, Lakshmanane; de Silva, Aravinda; Peters, Bjoern; Crotty, Shane; Sette, Alessandro; Weiskopf, Daniela

doi:10.1126/science.abd3871

Public

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

Published in Science • Aug 4, 2020

Authors:

José Mateus

Alba Grifoni

Alison Tarke

Abstract

Preexisting immune response to SARS-CoV-2 Robust T cell responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus occur in most individuals with coronavirus disease 2019 (COVID-19). Several studies have reported that some people who have not been exposed to SARS-CoV-2 have ...

Subject

Epitope

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Coronavirus disease 2019 (COVID-19)

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