Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells

Zhu, Na; Wang, Wenling; Liu, Zhidong; Liang, Chaoyang; Wang, Wen; Ye, Fei; Huang, Baoying; Zhao, Li; Wang, Huijuan; Zhou, Weimin; Deng, Yao; Mao, Longfei; Su, Chongyu; Qiang, Guangliang; Jiang, Taijiao; Zhao, Jincun; Wu, Guizhen; Song, Jingdong; Tan, Wenjie

doi:10.1038/s41467-020-17796-z

Public

Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells

Published in Nature Communications • Aug 6, 2020

Authors:

Na Zhu

Wenling Wang

Zhidong Liu

Abstract

SARS-CoV-2, a β-coronavirus, has rapidly spread across the world, highlighting its high transmissibility, but the underlying morphogenesis and pathogenesis remain poorly understood. Here, we characterize the replication dynamics, cell tropism and morphogenesis of SARS-CoV-2 in organotypic human airw...

Subject

Morphogenesis

Tropism

Biology

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