Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials

Pazan, Farhad; Petrović, Mirko; Cherubini, Antonio; Onder, Graziano; J. Cruz‐Jentoft, Alfonso; Denkinger, Michael; J. M. van der Cammen, Tischa; M Stevenson, Jennifer; Ibrahim, Kinda; Rajkumar, Chakravarthi; Stordal Bakken, Marit; Baeyens, Jean‐Pierre; Crome, Peter; Frühwald, Thomas; Gallaghar, Paul; Guðmundsson, Aðalsteinn; Knol, Wilma; O’Mahony, Denis; Pilotto, Alberto; Rönnemaa, Elina; Antonio Serra Rexach, José; Soulis, George; J. van Marum, Rob; Ziere, Gijsbertus; Mair, Alpana; Burkhardt, Heinrich; Neumann‐Podczaska, Agnieszka; Wieczorowska–Tobis, Katarzyna; Andreia Fernandes, Marília; Gruner, Heidi; Dallmeier, Dhayana; Beuscart, Jean‐Baptiste; van der Velde, Nathalie; Wehling, Martin

doi:10.1007/s00228-020-02951-8

Public

Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials

Published in European Journal of Clinical Pharmacology • Aug 7, 2020

Authors:

Farhad Pazan

Mirko Petrović

Antonio Cherubini

Abstract

BACKGROUND: Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest frailty. METHODS: A literature search was performed in Medline to detect prospecti...

Subject

Medicine

Psychological intervention

Polypharmacy

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