Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

S. Arunachalam, Prabhu; Wimmers, Florian; Ka Pun Mok, Chris; A. P. M. Perera, Ranawaka; Scott, Madeleine; Hagan, Thomas; Sigal, Natalia; Feng, Yupeng; Bristow, Laurel; Tak‐Yin Tsang, Owen; Wagh, Dhananjay; A. Coller, John; L. Pellegrini, Kathryn; Kazmin, Dmitri; Alaaeddine, Ghina; Leung, Wai-Shing; Man Chun Chan, Jacky; Shiu Hong Chik, Thomas; Yau Chung Choi, Chris; Huerta, Christopher; Paine McCullough, Michele; Lv, Huibin; J. Anderson, Evan; Edupuganti, Srilatha; A. Upadhyay, Amit; Bosinger, Steve; T. Maecker, Holden; Khatri, Purvesh; Rouphael, Nadine; Peiris, Malik; Pulendran, Bali

doi:10.1126/science.abc6261

Public

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

Published in Science • Aug 11, 2020

Authors:

Prabhu S. Arunachalam

Florian Wimmers

Chris Ka Pun Mok

Abstract

Coronavirus disease 2019 (COVID-19) represents a global crisis, yet major knowledge gaps remain about human immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We analyzed immune responses in 76 COVID-19 patients and 69 healthy individuals from Hong Kong and Atlanta, Georgia, U...

Subject

Coronavirus disease 2019 (COVID-19)

Immunity

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

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