Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for <i>CYP2C19</i> and Proton Pump Inhibitor Dosing

J. Lima, John; D. Thomas, Cameron; M. Barbarino, Julia; Desta, Zeruesenay; L. Van Driest, Sara; El Rouby, Nihal; A. Johnson, Julie; H. Cavallari, Larisa; Shakhnovich, Valentina; Thacker, David; A. Scott, Stuart; Schwab, Matthias; Rao S. Uppugunduri, Chakradhara; M. Formea, Christine; P. Franciosi, James; Sangkuhl, Katrin; Gaedigk, Andrea; E. Klein, Teri; S. Gammal, Roseann; Furuta, Takahisa

doi:10.1002/cpt.2015

Public

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing

Published in Clinical Pharmacology & Therapeutics • Aug 8, 2020

Authors:

John J. Lima

Cameron D. Thomas

Julia M. Barbarino

Abstract

Proton pump inhibitors (PPIs) are widely used for acid suppression in the treatment and prevention of many conditions, including gastroesophageal reflux disease, gastric and duodenal ulcers, erosive esophagitis, Helicobacter pylori infection, and pathological hypersecretory conditions. Most PPIs are...

Subject

CYP2C19

Proton-pump inhibitor

Medicine

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