Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer

Lin, Anqi; Zhang, Jian; Luo, Peng

doi:10.3389/fimmu.2020.02039

Public

Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer

Published in Frontiers in Immunology • Aug 12, 2020

Authors:

Anqi Lin

Jian Zhang

Peng Luo

Abstract

Colorectal cancer (CRC) patients, especially those with deficient mismatch repair (dMMR)/microsatellite instability-high (MSI-H) tumors, whose sensitivity to immune checkpoint inhibitors (ICIs) is significantly higher than that of patients with microsatellite-stable (MSS)/microsatellite instability-...

Subject

Microsatellite instability

Immune system

Immunotherapy

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