On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2

Sauvat, Allan; Ciccosanti, Fabiola; Colavita, Francesca; Di Rienzo, Martina; Castilletti, Concetta; Rosaria Capobianchi, Maria; Kepp, Oliver; Zitvogel, Laurence; María Fimia, Gian; Piacentini, Mauro; Kroemer, Guido

doi:10.1038/s41419-020-02842-x

Public

On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2

Published in Cell Death and Disease • Aug 19, 2020

Authors:

Allan Sauvat

Fabiola Ciccosanti

Francesca Colavita

Abstract

The current epidemic of coronavirus disease-19 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) calls for the development of inhibitors of viral replication. Here, we performed a bioinformatic analysis of published and purported SARS-CoV-2 antivirals including imatin...

Subject

Viral replication

Vero cell

Coronavirus

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