Children’s Oncology Group AALL0434: A Phase III Randomized Clinical Trial Testing Nelarabine in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia

P. Dunsmore, Kimberly; S. Winter, Stuart; Devidas, Meenakshi; L. Wood, Brent; Esiashvili, Natia; Chen, Zhiguo; Eisenberg, Nancy; Briegel, Nikki; J. Hayashi, Robert; M. Gastier‐Foster, Julie; J. Carroll, Andrew; A. Heerema, Nyla; L. Asselin, Barbara; R. Rabin, Karen; A. Zweidler‐McKay, Patrick; A. Raetz, Elizabeth; L. Loh, Mignon; R. Schultz, Kirk; Winick, Naomi; L. Carroll, William; P. Hunger, Stephen

doi:10.1200/jco.20.00256

Public

Children’s Oncology Group AALL0434: A Phase III Randomized Clinical Trial Testing Nelarabine in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia

Published in Journal of Clinical Oncology • Aug 19, 2020

Authors:

Kimberly P. Dunsmore

Stuart S. Winter

Meenakshi Devidas

Abstract

PURPOSE Nelarabine is effective in inducing remission in patients with relapsed and refractory T-cell acute lymphoblastic leukemia (T-ALL) but has not been fully evaluated in those with newly diagnosed disease. PATIENTS AND METHODS From 2007 to 2014, Children’s Oncology Group trial AALL0434 (Clinica...

Subject

Medicine

Internal medicine

Randomization

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