Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial.

A, Moskowitz; DT, Huang; PC, Hou; J, Gong; PB, Doshi; AV, Grossestreuer; LW, Andersen; L, Ngo; RL, Sherwin; KM, Berg; M, Chase; MN, Cocchi; JB, McCannon; M, Hershey; A, Hilewitz; M, Korotun; LB, Becker; RM, Otero; J, Uduman; A, Sen; MW, Donnino

doi:10.1001/jama.2020.11946

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Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial.

Shared by NobleBlocks on Aug 1, 2020 • 12:00 AM UTC

Authors:

Moskowitz A

Huang DT

Hou PC

Abstract

Importance The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock.Objective To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ injury in patients with septic shock.Design, setting,...

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