Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock

Moskowitz, Ari; T. Huang, David; C. Hou, Peter; Gong, Jonathan; Doshi, Pratik; V. Grossestreuer, Anne; W. Andersen, Lars; Ngo, Long; Sherwin, Robert; M. Berg, Katherine; Chase, Maureen; N. Cocchi, Michael; B. McCannon, Jessica; D. Hershey, Mark; Hilewitz, Ayelet; Korotun, Maksim; B. Becker, Lance; Otero, Ronny; Uduman, Junior; Sen, Ayan; W. Donnino, Michael

doi:10.1001/jama.2020.11946

Public

Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock

Published in JAMA • Aug 18, 2020

Authors:

Ari Moskowitz

David T. Huang

Peter C. Hou

Abstract

IMPORTANCE: The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock. OBJECTIVE: To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ injury in patients with septic shock. DESIGN, SETT...

Subject

Medicine

Ascorbic acid

Thiamine

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