Quercetin promotes human epidermal stem cell proliferation through the estrogen receptor/β-catenin/c-Myc/cyclin A2 signaling pathway

Wang, Zhaodong; Zhang, Guangliang; Le, Yingying; Ju, Jihui; Zhang, Ping; Wan, Dapeng; Zhao, Qiang; Jin, Guangzhe; Su, Hao; Liu, Jinwei; Feng, Jiaxuan; Fu, Yi; Hou, Ruixing

doi:10.1093/abbs/gmaa091

Public

Quercetin promotes human epidermal stem cell proliferation through the estrogen receptor/β-catenin/c-Myc/cyclin A2 signaling pathway

Published in Acta Biochimica et Biophysica Sinica • Jul 20, 2020

Authors:

Zhaodong Wang

Guangliang Zhang

Yingying Le

Abstract

Skin epidermal stem cells (EpSCs) play an important role in wound healing. Quercetin is a phytoestrogen reported to accelerate skin wound healing, but its effect on EpSCs is unknown. In this study, we investigated the effect of quercetin on human EpSC proliferation and explored the underlying mechan...

Subject

Endocrinology

Internal medicine

Chemistry

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