Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

Damas, Joana; M. Hughes, Graham; C. Keough, Kathleen; A. Painter, Corrie; S. Persky, Nicole; Corbo, Marco; Hiller, Michael; Koepfli, Klaus-Peter; R. Pfenning, Andreas; Zhao, Huabin; P. Genereux, Diane; Swofford, Ross; S. Pollard, Katherine; A. Ryder, Oliver; T. Nweeia, Martin; Lindblad-Toh, Kerstin; C. Teeling, Emma; K. Karlsson, Elinor; A. Lewin, Harris

doi:10.1073/pnas.2010146117

Public

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

Shared by NobleBlocks on Aug 21, 2020 • 12:00 AM UTC

Authors:

Joana Damas

Graham M. Hughes

Kathleen C. Keough

Abstract

Significance The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19, a major pandemic that threatens millions of human lives and the global economy. We identified a large number of mammals that can potentially be infected by SARS-CoV-2 via their ACE2 proteins...

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