Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19

Dequin, Pierre‐François; Heming, Nicholas; Meziani, Ferhat; Plantefève, Gaëtan; Voiriot, Guillaume; Badié, Julio; François, Bruno; Aubron, Cécile; Ricard, Jean-Damien; Ehrmann, Stéphan; Jouan, Youenn; Guillon, Antoine; Leclerc, M; Coffre, Carine; Bourgoin, Hélène; Lengellé, Céline; Caille-Fénérol, Caroline; Tavernier, Elsa; Zohar, Sarah; Giraudeau, Bruno; Annane, Djillali; Le Gouge, Amélie; COVID Trial Group and the CRICS-TriGGERSep Network, CAPE

doi:10.1001/jama.2020.16761

Public

Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19

Published in JAMA • Sep 2, 2020

Authors:

Pierre‐François Dequin

Nicholas Heming

Ferhat Meziani

Abstract

Importance: Coronavirus disease 2019 (COVID-19) is associated with severe lung damage. Corticosteroids are a possible therapeutic option. Objective: To determine the effect of hydrocortisone on treatment failure on day 21 in critically ill patients with severe acute respiratory syndrome coronavirus ...

Subject

Medicine

Mechanical ventilation

Extracorporeal membrane oxygenation

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