SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

Zhang, Si; Liu, Yangyang; Wang, Xiaofang; Li, Yang; Li, Haishan; Wang, Yuyan; Liu, Mengduan; Zhao, Xiaoyan; Xie, Youhua; Yang, Yan; Zhang, Shenghui; Fan, Zhichao; Dong, Jianzeng; Yuan, Zhenghong; Ding, Zhongren; Zhang, Yi; Hu, Liang

doi:10.1186/s13045-020-00954-7

Public

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

Published in Journal of Hematology & Oncology • Sep 4, 2020

Authors:

Si Zhang

Yangyang Liu

Xiaofang Wang

Abstract

BACKGROUND: Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic state that places them at a dramatically increased lethal risk. Although platelet activation is critical for thrombosis and is responsible for the thrombotic events and cardiovascular complications, the role of ...

Subject

Coronavirus disease 2019 (COVID-19)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Hematology

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